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glutamate receptor Hereditary syndromes with increased risk
2019-07-01

Hereditary syndromes with increased risk for gastric cancer include: 1) hereditary diffuse gastric cancer, 2) Lynch syndrome/hereditary non-polyposis colorectal cancer, 3) juvenile polyposis syndrome, 4) Peutz-Jeghers syndrome and 5) familial adenomatous polyposis. Hereditary diffuse gastric cancer
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Furegrelate sodium salt weight Cryotherapy related soft tiss
2019-07-01

Cryotherapy related soft tissue injury usually occurs within a few weeks postoperatively. Skin necrosis is a significant complication if freezing of the superficial surface occurs. Constant irrigation of the adjacent tissues with warm saline reduces the chance of skin necrosis. Our rate of infection
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We established Wt and two Mt p R
2019-07-01

We established Wt- and two Mt- (p.R308P and p.A350_N351ins8)-GATA2-expressing 32D Birinapant to analyze the cellular effects of Mt-GATA2 (Fig. 3A). Immunofluorescence analysis revealed that Mt-GATA2 showed similar localization in the nucleus as Wt-GATA2 (Fig. 3B). Both Wt- and mutant-GATA2-expressi
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Upon diagnosis the patient s lymphoma and
2019-07-01

Upon diagnosis, the patient׳s lymphoma and HLH represented a therapeutic dilemma. Effective early therapy reduces mortality of HLH from 95% to 30–35% [4]. The HLH-2004 treatment protocol consists of T-cell targeted immunosupression with dexamethasone and cyclosporine, macrophage targeted etoposide w
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Chronic myelomonocytic leukemia has been reported
2019-06-29

Chronic myelomonocytic leukemia has been reported as the most prevalent concomitant hematological neoplasm, followed by myelodysplastic, myeloproliferative syndrome, and acute myeloid leukemia; on the other hand, Lymphoproliferative neoplasms were less frequency associated with SM-AHMND. In another
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br Basis and methodology of DCE MRI DCE MRI images
2019-06-29

Basis and methodology of DCE-MRI DCE-MRI images are performed by using injecting low-molecular-weight gadolinium chelated contrast agent with a constant, stable rate. The contrast agent is carried by blood flow into the tissue, causing increased signal intensity (SI) of the T1-weighted images due
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Lead fracture was observed in of leads verified and incomple
2019-06-29

Lead fracture was observed in 4 of 1092 leads (0.37%); verified and incomplete lead fractures were observed in three (0.27%) and one lead (0.09%), respectively. All these fractures occurred in leads implanted by the SVP method; no fractures were observed in leads implanted by the CVC method (p Disc
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Concern about the effects on health of
2019-06-29

Concern about the effects on health of chemical exposure to e-waste and e-waste recycling is increasing despite the paucity of solid research. Reported adverse effects include: fetal loss, prematurity, low birthweight, and congenital malformations; abnormal thyroid function and thyroid development;
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In addition we are continuing
2019-06-29

In addition, we are continuing our regular editorial policies of commissioning more specialised Clinical Reviews and Series across Group to provide a more focused and in-depth assessment for key diseases. And beyond providing knowledge and information, we want to encourage academic and practising c
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Se temos ent o um passado colonial comum
2019-06-29

Se temos, então, um passado Chlorocresol comum e uma gente que “sobreviveu a séculos de genocídio”, parece ser a língua portuguesa e as trocas comerciais direcionadas para os Estados Unidos e para a Europa que nos isolam, como se disséssemos: “Não trabalhamos com pobres como nós”, “Apesar da pobrez
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br Role of the funding
2019-06-29

Role of the funding source Contributions Conflicts of interest Acknowledgments The authors would like to thank the patients who participated in this study and their families. The authors would also like to acknowledge the writing assistance of Stephen Mosley, Ph.D., of Knowledge Point 36
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Preventive chemotherapy for schistosomiasis is rapidly scali
2019-06-29

Preventive chemotherapy for schistosomiasis is rapidly scaling up worldwide. The global coverage that was less than 10% in 2010 is now higher than 30%, however, the main limitation for the scaling up is the availability of donated drug. In school age children, the age group for which praziquantel is
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Sin embargo m s all de las coincidencias sobre
2019-06-28

Sin embargo, más allá de las coincidencias sobre qué hacer con y en el exilio, las significativas posiciones que se presentaron en sus páginas estuvieron lejos de mantener una posición unívoca. Como sugirió Gago, en Controversia pueden reconocerse al menos tres figuras: (1) el exilio como privilegio
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br Discussion There is an
2019-06-28

Discussion There is an important need for new treatment options for AML in elderly patients. Their frailty imposes limitations upon the aggressiveness of the treatment which can be administered [6,24]. In addition, the poor prognostic disease features often seen in this CGK733 mean that refractor
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br For more than a decade WHO has focused its
2019-06-28

For more than a decade, WHO has focused its efforts against infectious diseases in Africa on HIV, tuberculosis, and malaria. HIV benefited from unprecedented efforts to enable diagnosis and prevention of transmission and to provide therapy at low cost. National networks of health clinics, transpor
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