• Whether histamine receptor distribution is altered in canine

  2022-06-18

  

  Whether histamine receptor distribution is altered in canine GI diseases remains unknown, but human research has documented altered histamine receptor density in certain GI diseases (Sander et al., 2006, Deiteren et al., 2015, Von Rahden et al., 2011). Additionally, a novel H4 receptor antagonist, J

• To promote biomimetic growth of HAp Li et al developed

  2022-06-18

  

  To promote biomimetic growth of HAp, Li et al. [20] developed a technique to modify cellulose nanofibers using P2O5. It was ascertained that the negative phosphate groups bonded with Ca2+ through coordination bonds and subsequently guided the growth of the Ca–P crystals throughout the scaffolds. Sim

• br Conflict of interest br Funding br

  2022-06-18

  

  Conflict of interest Funding Introduction Heme is an essential molecule for cellular metabolism involving oxygen and electron transfer [1]. However, free heme is a potent pro-oxidant that catalyzes the generation of reactive oxygen species (ROS) leading to cellular damage [2]. Heme oxygenas

• br Introduction Adipose tissue AT in addition to its

  2022-06-17

  

  Introduction Adipose tissue (AT), in addition to its function as N6-Methyl-ATP storage, is an important endocrine organ and it secretes adipokines (Ahima, 2006). Adipose tissue is related to different physiological processes such as energy metabolism, insulin sensitivity, and inflammation. One im

• Shikonin represents naphtoquinonic compound isolated from th

  2022-06-17

  

  Shikonin represents naphtoquinonic compound isolated from the Chinese plant Lithospermum erythrorhizon[20]. Shikonin treatment inhibits AKT and ERK signaling pathways and induces apoptosis through FOXO transcription factors and mitochondrial pathway [21], [22]. Recent results suggest inhibition of l

• br Declaration of interest br Acknowledgments

  2022-06-17

  

  Declaration of interest Acknowledgments This work was financially supported by the National Natural Science Foundation of China (No. 31471615), the Introduction of Talent Research Start-up Fund of Anhui Polytechnic University (No. 2017YQQ017) and the Pre-research Project of National Natural Sc

• Pancuronium dibromide br Origin of the vertebrate hexokinase

  2022-06-17

  

  Origin of the vertebrate hexokinase gene family Multiple hexokinases have been found in vertebrates, plants and yeast (Wilson, 1995, Cárdenas et al., 1998). A hexokinase in both vertebrates and yeast has, unfortunately, been named glucokinase. The sharing of the name glucokinase has suggested to

• br Conclusions Temporally controlled disruption of

  2022-06-17

  

  Conclusions Temporally-controlled disruption of Gcgr reveals a lack meaningful contribution to the improvement of glycemic control in insulinopenic conditions attributable to the intrinsic loss of GCGR signaling. On the other hand, these data highlight the importance of compensatory systems, incl

• hcv virus br Introduction Connexins are transmembrane

  2022-06-17

  

  Introduction Connexins are transmembrane proteins that allow the exchange of molecules with the extracellular environment or adjacent hcv virus via channels in the plasma membrane. Intercellular communication and exchange of biologically active molecules, salts, and nutrients to the extracellula

• Based on the above considerations the galactosidase gene fro

  2022-06-17

  

  Based on the above considerations, the β-galactosidase gene from Exiguobacterium acetylicum MF03 (not previously reported) was cloned, expressed and purified with the aim of assessing the potential of this novel enzyme for catalyzing reactions of synthesis and hydrolysis of glycosides. Because of E.

• br Materials and Methods br Results br

  2022-06-17

  

  Materials and Methods Results Discussion In the present study, we investigated the postnatal expression of the two GABA receptor subunits, GABAAα1 and GABAB1, in order to determine the differential expression and regional distribution pattern of them between right and left hippocampi in the

• Introduction Initially postulated to represent the main sour

  2022-06-17

  

  Introduction Initially postulated to represent the main source of ATP production in eukaryotic cells, mitochondria are recently recognized to perform manifold essential functions beyond energy production, impacting most areas of cell biology and medicine [1]. Mitochondrial metabolism is both the ba

• Pam2CSK4 receptor In Apicomplexan parasites such as Toxoplas

  2022-06-17

  

  In Apicomplexan parasites such as Toxoplasma gondii isoprenoids are biosynthesized through the DOXP/MEP pathway as illustrated in Scheme 2. In addition, T. gondii possesses a bifunctional FPPS/GGPPS (TgFPPS) that is able to catalyze the formation of both FPP and GGPP.5, 6 The FPPS gene appears to be

• The organ culture method has previously shown to be

  2022-06-16

  

  The organ culture method has previously shown to be a suitable model for investigations of receptor upregulation on vascular smooth muscle cells (Adner et al., 1996). In our study, the organ culture method was applied in order to examine whether LPS from P.g. was capable of altering the gene express

• The more important effect of pitolisant is

  2022-06-16

  

  The more important effect of pitolisant is related to its wake-promoting and arousal activities as a result of enhanced Ro 31-8220 release in animal models (Ligneau, Perrin, et al., 2007). Moreover, its potential in the treatment of severe excessive daytime sleepiness (EDS) in narcoleptic teenagers

11892 records 142/793 page Previous Next First page 上5页 141142143144145 下5页 Last page